Influenza A infection history and antibody response

originally published online on March 16, 2015 at https://www.jonzelner.net/

I just came across this paper by Adam Kucharski and co. using cross-sectional antibody titer data to understand the relationship between the ordering of influenza A infections and long-term antibody response, as well as the rate of decay in cross-reactivity in neutralizing responses.

Even though the whole flu world is a bit outside of my own personal wheelhouse, I’m a big fan of anything that extracts temporal information out of cross-sectional data, and thought this paper was a pretty excellent example of making the most of cross-sectional data and also highlights a pretty amazing dataset from a survey of antibody titers against influenza strains from 1968 to 2009 in southern China.

Jon Zelner
Jon Zelner
Assistant Professor

My research interests include distributed robotics, mobile computing and programmable matter.